Description

Hydrocortisone 17-Propionate is a synthetic corticosteroid ester, specifically a 17-propionate derivative of hydrocortisone. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, offering a critical building block for advanced pharmaceutical formulations. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of topical corticosteroids and other therapeutic agents.

Application

• Active Pharmaceutical Ingredient (API) for topical corticosteroid creams, ointments, and lotions.
• Pharmaceutical Intermediate in the synthesis of more complex steroid-based drugs.
• Reference Standard for analytical testing and quality control in pharmaceutical laboratories.
• Research & Development tool for studying glucocorticoid receptor activity and inflammatory pathways.
• Formulation Development for dermatological products targeting eczema, psoriasis, and dermatitis.

Basic Information

Product Name	Hydrocortisone 17-Propionate
CAS No.	65980-97-4
Molecular Formula	C24H34O6
Molecular Weight	418.52 g/mol
Synonyms	Hydrocortisone 17-propionate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 17-propionate; Cortisol 17-propionate; Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, 17-propanoate; Hydrocortisone propionate (17-); 17α-Hydroxycorticosterone 17-propionate
EINECS	Contact for details

Quality Control

Our Hydrocortisone 17-Propionate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to guarantee supply reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.