Description

Ethynylmagnesium Chloride is a highly reactive organometallic compound, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the introduction of the ethynyl (acetylene) group, enabling the construction of complex molecular architectures. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is utilized for carbon-carbon bond formation and the synthesis of key intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing acetylene functionalities into drug candidates, particularly in oncology and antiviral research.
• Agrochemical Production: Used in the manufacture of advanced pesticides and herbicides that require acetylene-based active ingredients.
• Fine Chemical & Specialty Chemical Synthesis: Employed in the production of complex organic molecules, including dyes, fragrances, and liquid crystals.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and conductive materials.
• Academic & R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.
• Synthesis of Natural Products: Facilitates the construction of complex natural product skeletons that contain alkyne moieties.

Basic Information

Product Name	Ethynylmagnesium Chloride
CAS No.	65032-27-1
Molecular Formula	C2HClMg
Molecular Weight	92.68 g/mol
Synonyms	Magnesium, chloromethylacetylide; Chloro(ethynyl)magnesium; Ethynylmagnesium chloride solution; Acetylenylmagnesium chloride; Magnesium acetylide chloride; Ethynyl Grignard reagent; HC≡CMgCl
EINECS	Contact for details

Quality Control

Our Ethynylmagnesium Chloride is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for assay determination and GC analysis for solvent and impurity profiling, to ensure consistency and high reactivity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated area, away from heat, moisture, and oxidizing agents. Due to its highly volatile and pyrophoric nature in certain concentrations, handle only in a controlled environment with appropriate safety measures.

Specification

Item	Specification
Appearance	Solution in specified solvent (e.g., THF, Diethyl ether)
Assay (by Titration)	0.5 M in THF (Typical, other concentrations available)
Purity (GC)	≥ 95% (relative area)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.