Description

N1-[3-[[2-(2-Pyridyl)Ethyl]Amino]Propyl]Bleomycinamide is a chemically modified bleomycin derivative, representing a key intermediate in the development of targeted anticancer agents and research tools. Its value lies in its role as a precise building block for creating novel conjugates that enhance drug specificity and reduce systemic toxicity. This compound is essential for pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on oncology drug discovery and advanced bioconjugation studies.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of next-generation bleomycin-based chemotherapeutic agents and antibody-drug conjugates (ADCs).
• Oncology Research: Used as a model compound in biochemical studies to investigate DNA cleavage mechanisms and cellular uptake pathways.
• Bioconjugation Probe: Serves as a functionalized linker for attaching cytotoxic payloads to targeting molecules like peptides, antibodies, or nanoparticles.
• Mechanistic Studies: Employed in academic and industrial labs to study structure-activity relationships (SAR) within the bleomycin family of antibiotics.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical manufacturing.

Basic Information

Product Name	N1-[3-[[2-(2-Pyridyl)Ethyl]Amino]Propyl]Bleomycinamide
CAS No.	61949-96-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[3-[[2-(2-pyridinyl)ethyl]amino]propyl]-; BLM Derivative; PEB-Bleomycin; 3-[(2-Pyridin-2-ylethyl)amino]propyl-bleomycinamide; Bleomycin A2 derivative; N1-(3-((2-(Pyridin-2-yl)ethyl)amino)propyl)bleomycinamide
EINECS	Contact for details

Quality Control

Our N1-[3-[[2-(2-Pyridyl)Ethyl]Amino]Propyl]Bleomycinamide is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.