Description

(7S,9S)9-Acetyl-7,8,9,10-Tetrahydro-6,7,9,11-Tetrahydroxy-5,12-Naphtacenedione is a high-purity, structurally defined anthracycline derivative, essential for advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate and reference standard for the synthesis and analytical characterization of complex bioactive molecules. It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in oncology drug discovery and the production of specialized chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex anthracycline-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical laboratories.
• Biochemical Research: Serves as a precursor or model compound in studies of DNA intercalation and topoisomerase inhibition mechanisms.
• Oncology Drug Discovery: Utilized in the research and development of novel chemotherapeutic agents and targeted therapies.
• Fine Chemical Synthesis: Intermediate for the preparation of other specialized, high-value tetrahydroxynaphtacenedione derivatives.

Basic Information

Product Name	(7S,9S)9-Acetyl-7,8,9,10-Tetrahydro-6,7,9,11-Tetrahydroxy-5,12-Naphtacenedione
CAS No.	60660-75-5
Molecular Formula	C₂₀H₁₈O₈
Molecular Weight	386.35 g/mol
Synonyms	9-Acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-5,12-naphthacenedione; (7S,9S)-9-Acetyltetrahydro-6,7,9,11-tetrahydroxy-5,12-naphthacenedione; 9-Acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxynaphthacene-5,12-dione; Aclarubicin derivative; Anthracycline intermediate; Tetrahydroxynaphtacenedione derivative
EINECS	Contact for details

Quality Control

Our (7S,9S)9-Acetyl-7,8,9,10-Tetrahydro-6,7,9,11-Tetrahydroxy-5,12-Naphtacenedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets stringent specifications for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.