Description

tert-Butylmagnesium Chloride is a highly reactive organomagnesium compound, widely recognized as a Grignard reagent. It serves as a critical building block in organic synthesis, enabling the efficient introduction of the tert-butyl group into target molecules. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable carbon-carbon bond formation.

Application

• Pharmaceutical Intermediates: Key reagent for synthesizing complex drug molecules, particularly in the construction of sterically hindered tertiary carbon centers.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the tert-butyl moiety imparts specific biological activity and stability.
• Polymer & Material Science: Employed as an initiator or modifying agent in the development of specialty polymers and functional materials.
• Fine Chemical Production: Facilitates alkylation and nucleophilic addition reactions in the synthesis of flavors, fragrances, and other high-value chemicals.
• Laboratory Research: A staple reagent in academic and industrial R&D for method development and small-scale synthesis of novel organic compounds.
• Catalyst Ligand Precursor: Used to prepare magnesium-based catalysts or as a source of the tert-butyl ligand in organometallic chemistry.

Basic Information

Product Name	tert-Butylmagnesium Chloride
CAS No.	677-22-5
Molecular Formula	C4H9ClMg
Molecular Weight	116.87 g/mol
Synonyms	tert-Butylmagnesium chloride; Magnesium, chlorotert-butyl-; Chloro(tert-butyl)magnesium; (tert-Butyl)magnesium chloride; t-BuMgCl; Grignard reagent, tert-butylmagnesium chloride; tert-Butyl magnesium chloride; 1,1-Dimethylethylmagnesium chloride
EINECS	211-642-4

Quality Control

Our tert-Butylmagnesium Chloride is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including titration for assay determination and gas chromatography (GC) to monitor solvent and impurity profiles. We provide Certificates of Analysis (COA) with every shipment, detailing purity, concentration, and key parameters to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and easily oxidized (store under inert atmosphere). For optimal stability, store under a dry, inert gas (argon or nitrogen) at 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as water, acids, and oxidizing agents. Use only in a well-ventilated area with appropriate safety equipment.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in solvent)	Typically 1.0 M in Diethyl Ether or 2.0 M in Tetrahydrofuran
Assay (by Titration)	≥ 95% (as tert-BuMgCl)
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.