Description

N1-(3-(Methylsulfinyl)Propyl)Bleomycinamide is a chemically modified derivative of the bleomycin family of glycopeptide antibiotics. This compound is significant for its role as a key intermediate in pharmaceutical research and development, particularly in the synthesis of novel anti-tumor agents and for structure-activity relationship (SAR) studies. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology drug discovery and advanced therapeutic development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel bleomycin analogs and conjugates for cancer therapy research.
• Biochemical Research: Used in mechanistic studies to investigate DNA cleavage activity and the role of the bleomycin metal-binding domain.
• Antitumor Agent Development: A key precursor for developing next-generation chemotherapeutic agents with potentially improved efficacy or reduced side effects.
• Academic Research: Employed in university and institutional labs for studying glycopeptide antibiotic chemistry and mode of action.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control in related API manufacturing.
• Drug Discovery Programs: Integrated into screening libraries and medicinal chemistry campaigns targeting DNA-damaging agents.

Basic Information

Product Name	N1-(3-(Methylsulfinyl)Propyl)Bleomycinamide
CAS No.	58995-26-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bleomycinamide, N1-[3-(Methylsulfinyl)propyl]-; Bleomycin derivative; 3'-(Methylsulfinyl)propylamine bleomycinamide; N1-(3-Methylsulfinylpropyl)bleomycinamide; Bleomycin A2 amide derivative; (3-Methylsulfinylpropyl)bleomycinamide; Research Compound 58995-26-9
EINECS	Contact for details

Quality Control

Our N1-(3-(Methylsulfinyl)Propyl)Bleomycinamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by HPLC to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.