Description

2-Bromobenzylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone intermediate in advanced organic synthesis. Its value lies in its ability to introduce the 2-bromobenzyl group, enabling the construction of complex molecular architectures with high precision. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides requiring specific aromatic substitutions.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers with tailored properties.
• Cross-Coupling Reactions: A vital reagent in Kumada and other transition-metal-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance, flavor, and dye molecules.

Basic Information

Product Name	2-Bromobenzylmagnesium Bromide
CAS No.	56812-60-3
Molecular Formula	C7H6Br2Mg
Molecular Weight	274.23 g/mol
Synonyms	(2-Bromobenzyl)magnesium Bromide; 1-(Bromomethyl)-2-bromobenzene Magnesium Bromide Salt; Magnesium, bromo(2-bromophenyl)methyl-; 2-Bromobenzylmagnesium Bromide Solution; o-Bromobenzylmagnesium Bromide; Grignard Reagent from 1-Bromo-2-(bromomethyl)benzene
EINECS	Contact for details

Quality Control

Our 2-Bromobenzylmagnesium Bromide is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, concentration (typically supplied in standard ethereal solvents like THF or diethyl ether), and impurity profiles. We adhere to relevant industry standards, and custom purity grades, including research and development or cGMP-compliant materials, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For solutions, store at recommended temperatures (typically 2-8°C or as specified) and away from moisture, heat, and incompatible materials such as acids, oxidizers, and protic solvents.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Concentration	Typically 0.5 M to 2.0 M in THF or Et2O
Assay (Titration)	≥ 95% (as Grignard reagent)
Identification (IR/NMR)	Conforms to structure
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.