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2-Cyclohexylethylmagnesium Bromide CAS NO 55766-17-1
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CAS No.:55766-17-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Cyclohexylethylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis for the formation of carbon-carbon bonds. Its value lies in its ability to introduce the 2-cyclohexylethyl moiety into target molecules, enabling the synthesis of complex intermediates for pharmaceuticals and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel molecular architectures.
Application
- Pharmaceutical Intermediate Synthesis: Key reagent for constructing carbon skeletons in active pharmaceutical ingredients (APIs), particularly for introducing lipophilic cyclohexyl-containing side chains.
- Agrochemical Manufacturing: Used in the production of advanced pesticides and herbicides where the cyclohexylethyl group imparts specific biological activity and stability.
- Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, fragrances, and advanced polymer precursors.
- Material Science Research: Facilitates the creation of novel organic compounds for electronic materials, liquid crystals, and other functional materials.
- Academic & R&D Laboratories: A fundamental tool for methodological development and exploratory synthesis in organic chemistry research.
- Nucleophilic Addition Reactions: Primarily used for addition to carbonyl groups (aldehydes, ketones, esters) to form secondary or tertiary alcohols.
Basic Information
| Product Name | 2-Cyclohexylethylmagnesium Bromide |
| CAS No. | 55766-17-1 |
| Molecular Formula | C8H15BrMg |
| Molecular Weight | 215.41 g/mol |
| Synonyms | (2-Cyclohexylethyl)magnesium bromide; Cyclohexaneethanamine, N-Mg-Br derivative; Magnesium, bromo(2-cyclohexylethyl)-; Grignard reagent, 2-cyclohexylethylmagnesium bromide; (Cyclohexylethyl)magnesium bromide; 2-Cyclohexyl-ethyl-magnesium bromide; Bromo(2-cyclohexylethyl)magnesium |
| EINECS | Contact for details |
Quality Control
Our 2-Cyclohexylethylmagnesium Bromide is manufactured under strict quality control protocols, typically supplied as a solution in tetrahydrofuran or diethyl ether. Each batch is analyzed to ensure high reactivity and consistency. Certificates of Analysis (COA) detailing concentration (by titration), purity, and solvent content are provided to guarantee it meets the rigorous standards required for sensitive synthetic applications. We adhere to cGMP principles where applicable to support our clients in regulated industries.
Storage
Preserve in a tightly closed container, protected from light. This product is highly reactive, hygroscopic (moisture-sensitive), easily oxidized, and highly volatile. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. Recommended storage temperature is typically 2-8°C for extended stability, though specific conditions depend on the solvent. Always refer to the specific material safety data sheet (MSDS) for detailed handling and storage instructions.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to light yellow solution |
| Concentration (in THF or Et2O) | 0.5 M - 2.0 M (Custom concentrations available) |
| Assay (Titration) | ≥ 95% |
| Identification (IR/NMR) | Conforms to structure |
| Solvent | Specified (Tetrahydrofuran or Diethyl ether) |
| Water Content (Karl Fischer) | < 100 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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