Description

Polydeoxy(Guanine-Thymine) Nucleotide is a synthetic oligonucleotide composed of alternating deoxyguanine and deoxythymine bases. This compound is a critical research-grade biochemical for studying nucleic acid structure, stability, and hybridization dynamics. It is primarily utilized by biotechnology, pharmaceutical, and academic research institutions for applications in molecular biology, diagnostic assay development, and as a model system for biophysical studies.

Application

• Molecular Biology Research: Used as a primer, probe, or template in PCR, sequencing, and hybridization experiments.
• Biophysical Studies: Serves as a model oligonucleotide for investigating DNA duplex stability, melting temperature (Tm), and secondary structure formation.
• Diagnostic Development: Acts as a key component in the design and validation of diagnostic kits and biosensors.
• Pharmaceutical R&D: Employed in antisense oligonucleotide research and early-stage therapeutic discovery programs.
• Quality Control Standard: Used as a reference standard in analytical laboratories to calibrate instruments and validate methods for nucleic acid analysis.
• Biochemical Reagent: Functions as a substrate or inhibitor in enzymatic studies involving nucleases, polymerases, and ligases.

Basic Information

Product Name	Polydeoxy(Guanine-Thymine) Nucleotide
CAS No.	55684-98-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(dG-dT); Poly(deoxyguanylic-deoxythymidylic) acid; Poly(dG-dT) oligonucleotide; Alternating dG-dT polymer; Poly(deoxyguanylate-deoxythymidylate); d(GT)n oligonucleotide; Oligo(dG-dT); Deoxyguanylyl-thymidylyl polymer
EINECS	Contact for details

Quality Control

Our Polydeoxy(Guanine-Thymine) Nucleotide is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Absorbance Ratio (A260/A280)	1.8 - 2.0
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.