Description

Poly(7-Deazainosinic Acid) is a synthetic polynucleotide analog derived from 7-deazainosine, a modified nucleoside. This compound is of significant interest in biochemical and pharmaceutical research due to its unique structural properties that affect nucleic acid interactions and stability. It serves as a critical tool for researchers in nucleic acid chemistry, molecular biology, and drug discovery, particularly in the development of oligonucleotide-based therapeutics and diagnostic probes.

Application

• Oligonucleotide Synthesis: Used as a modified building block for creating oligonucleotides with enhanced nuclease resistance and altered binding properties.
• Antisense and siRNA Research: A key component in the development of antisense oligonucleotides and small interfering RNA (siRNA) for gene silencing applications.
• Diagnostic Probe Development: Employed in the design of fluorescent probes and molecular beacons for nucleic acid detection and analysis.
• Structural Biology Studies: Utilized to investigate the structure, stability, and function of nucleic acids and their complexes with proteins.
• Therapeutic Agent Research: Investigated for potential use in the development of aptamers and other oligonucleotide-based pharmaceuticals.
• Biochemical Assay Reagent: Acts as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.

Basic Information

Item	Detail
Product Name	Poly(7-Deazainosinic Acid)
CAS No.	53794-83-5
Molecular Formula	(C10H11N4O7P)n
Molecular Weight	Contact for details
Synonyms	Poly(7-deazainosinic acid); Poly(tubercidin phosphoric acid); Poly(7-aza-7-deazainosinic acid); 7-Deazainosinic Acid Homopolymer; Poly(7-CI-inosinic acid) (related); Polynucleotide analog of tubercidin; Poly(7-deaza-inosinic acid); Poly(7-deaza-IMP)
EINECS	Contact for details

Quality Control

Our Poly(7-Deazainosinic Acid) is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (UV, IR), and assessment of polynucleotide chain length. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality system is designed to meet the exacting standards required for pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere or at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
UV-Vis Spectrum	Characteristic of 7-deazainosine derivative
Solubility	Soluble in aqueous buffers, DMSO
Water Content (KF)	< 5.0 %
Endotoxin	< 10 EU/mg (if for biological use)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.