Description

Butoxychloromagnesium is a versatile organomagnesium reagent, also known as butylmagnesium chloride, widely used in synthetic organic chemistry. Its primary value lies in its role as a highly effective nucleophile and strong base for the formation of carbon-carbon bonds, crucial for constructing complex molecular frameworks. This compound is essential for research laboratories and industrial-scale production in the pharmaceutical, agrochemical, and specialty chemical sectors, where it facilitates Grignard reactions and other critical synthetic transformations.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing butyl groups and constructing complex carbon skeletons in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and pesticides that require specific alkyl chain modifications.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and advanced materials where precise Grignard chemistry is required.
• Polymer Chemistry: Acts as an initiator or catalyst in the polymerization of certain monomers and in the modification of polymer chains.
• Academic & Industrial R&D: A fundamental tool in research laboratories for methodological development and the synthesis of novel organic compounds.
• Cross-Coupling Reactions: Serves as an organometallic coupling partner in reactions such as Kumada coupling for biaryl synthesis.

Basic Information

Product Name	Butoxychloromagnesium
CAS No.	53394-84-6
Molecular Formula	C₄H₉ClMg
Molecular Weight	116.87 g/mol
Synonyms	Butylmagnesium Chloride; Chloro(butyl)magnesium; Magnesium, butylchloro-; Butylmagnesium Chloride Solution; ButMgCl; n-Butylmagnesium Chloride; 1-Butylmagnesium Chloride; Butyl Chloromagnesium
EINECS	Contact for details

Quality Control

Our Butoxychloromagnesium is produced under stringent quality management systems to ensure batch-to-batch consistency and high reactivity. Typical quality parameters include concentration (as a solution in THF or diethyl ether), active magnesium content, and the absence of protic impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and reacts with strong acid/organic solvent. For solutions, store under a dry, inert atmosphere (argon or nitrogen) in a cool, well-ventilated area, away from heat, sparks, and open flames. Keep the container tightly sealed to exclude moisture and air. Refer to the Safety Data Sheet (SDS) for complete handling and storage instructions.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow liquid
Concentration (in THF)	1.0 M - 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95.0% (as Butylmagnesium Chloride)
Identification (IR)	Conforms to structure
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.