Description

Bromomagnesium Diethylamide is a highly reactive organomagnesium reagent, specifically a magnesium amide base. This compound is a powerful, non-nucleophilic base critical for deprotonation reactions in advanced organic synthesis. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and efficient generation of enolates or other carbanions under mild conditions.

Application

• As a strong, non-nucleophilic base for the regioselective deprotonation of sensitive carbonyl compounds.
• Key reagent in the synthesis of complex pharmaceutical intermediates, particularly for sterically hindered enolates.
• Facilitates halogen-metal exchange reactions in the preparation of functionalized organometallics.
• Used in the development of active ingredients for agrochemicals and fine chemicals.
• Employed in polymer chemistry for initiating anionic polymerizations of specific monomers.
• Essential for academic and industrial R&D in methodologies involving magnesium-amide chemistry.

Basic Information

Product Name	Bromomagnesium Diethylamide
CAS No.	5856-91-7
Molecular Formula	C4H10BrMgN
Molecular Weight	176.33 g/mol
Synonyms	Diethylaminomagnesium Bromide; Magnesium, bromo(N,N-diethylamide)-; Bromo(diethylamido)magnesium; (Diethylamino)magnesium Bromide; Et2NMgBr; Grignard Base (Diethylamide); LDA Magnesium Bromide Analog
EINECS	Contact for details

Quality Control

Our Bromomagnesium Diethylamide is produced under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, reactivity, and solution concentration. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Store in a cool, dry, well-ventilated area. For long-term stability, storage at 2-8°C is recommended.

Specification

Item	Specification
Appearance	Solution in specified solvent (e.g., THF, Et2O)
Concentration	0.5 M - 2.0 M in specified solvent (Typical)
Assay (Titration)	≥ 95% (as Bromomagnesium Diethylamide)
Identity (IR / NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.