Description

16-Methylepihydrocortisone CAS NO 514-55-6 is a synthetic corticosteroid derivative, a key intermediate in the synthesis of more complex steroid-based pharmaceuticals. Its value lies in providing a versatile and high-purity building block for research and development in the pharmaceutical industry. This compound is primarily needed by manufacturers and research institutions focused on developing novel anti-inflammatory, immunosuppressive, and dermatological treatments.

Application

• As a critical pharmaceutical intermediate in the synthesis of advanced corticosteroid drugs.
• Used in research and development for creating new anti-inflammatory and immunosuppressive agents.
• Serves as a reference standard or starting material in analytical chemistry and quality control laboratories.
• Potential use in the development of veterinary medicines for inflammatory conditions.
• Employed in academic research to study steroid metabolism and receptor interactions.
• As a precursor in the synthesis of specialized dermatological preparations.

Basic Information

Product Name	16-Methylepihydrocortisone
CAS No.	514-55-6
Molecular Formula	C₂₂H₃₀O₅
Molecular Weight	374.47 g/mol
Synonyms	16-Methylpregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-; 16-Methyl-11-dehydrocorticosterone; 16-Methyl-δ¹-dehydrocorticosterone; 16-Methyl-11-oxoprogesterone; 16-Methyl-17α,21-dihydroxypregna-1,4-diene-3,11,20-trione; 16-Methylepihydrocortisone; 16-Methyl-11-dehydrocorticosterone
EINECS	208-184-5

Quality Control

Our 16-Methylepihydrocortisone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.