Description

2-Methoxybenzylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, essential for introducing the 2-methoxybenzyl moiety into complex molecular frameworks. Its value lies in enabling critical carbon-carbon bond formation reactions, which are fundamental to constructing advanced pharmaceutical intermediates and fine chemicals. This high-purity reagent is primarily needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable and scalable synthetic solutions.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with benzyl ether or substituted benzyl structures.
• Agrochemical Development: Used in the research and manufacturing of advanced crop protection agents and herbicides.
• Fine Chemical Production: Employed in the synthesis of complex organic molecules, dyes, and fragrances requiring precise functionalization.
• Material Science Research: Serves as a precursor for creating novel organic ligands and polymers with specific electronic or structural properties.
• Academic & Industrial R&D: A critical tool for method development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Methoxybenzylmagnesium Chloride
CAS No.	480438-46-8
Molecular Formula	C8H9ClMgO
Molecular Weight	180.91 g/mol
Synonyms	(2-Methoxybenzyl)magnesium chloride; o-Methoxybenzylmagnesium chloride; 1-(Chloromagnesio)methyl-2-methoxybenzene; 2-Methoxybenzyl Grignard Reagent; 2-Methoxybenzylmagnesium Chloride Solution; (2-Methoxyphenyl)methylmagnesium chloride; Magnesium, chloro[(2-methoxyphenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 2-Methoxybenzylmagnesium Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm concentration, purity, and suitability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, titration results, and solvent specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For solutions, store as recommended by the specific solvent system, typically between 2°C and 8°C. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.