Description

(1,3-Dioxan-2-Ylethyl)Magnesium Bromide is a highly reactive organomagnesium reagent, specifically a Grignard reagent, widely used in advanced organic synthesis. Its core value lies in its ability to act as a powerful nucleophile and carbon nucleophile source for the formation of carbon-carbon bonds, a fundamental transformation in constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is employed in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and novel materials.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the (1,3-dioxan-2-ylethyl) moiety into target molecules during the research and development of new drug candidates.
• Nucleophilic Addition Reactions: Used in Grignard reactions with carbonyl compounds (aldehydes, ketones, esters) to produce secondary and tertiary alcohols.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic compounds for agrochemicals, flavors, and fragrances.
• Polymer Chemistry: Can serve as an initiator or functional group provider in the synthesis of specialized polymers and functional materials.
• Academic & Industrial R&D: A valuable tool in methodological development and exploratory chemistry within university and corporate research laboratories.

Basic Information

Item	Details
Product Name	(1,3-Dioxan-2-Ylethyl)Magnesium Bromide
CAS No.	480438-44-6
Molecular Formula	C7H13BrMgO2
Molecular Weight	233.39 g/mol
Synonyms	2-(1,3-Dioxan-2-yl)ethylmagnesium bromide; (2-(1,3-Dioxan-2-yl)ethyl)magnesium bromide; 1,3-Dioxan-2-ylethylmagnesium bromide; Grignard reagent from 2-(2-bromoethyl)-1,3-dioxane; 2-(2-Bromoethyl)-1,3-dioxane magnesium reagent; (1,3-Dioxan-2-ylethyl)magnesium bromide solution; 2-(1,3-Dioxan-2-yl)ethylmagnesium bromide solution
EINECS	Contact for details

Quality Control

Our (1,3-Dioxan-2-Ylethyl)Magnesium Bromide is manufactured under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including titration for active Grignard concentration and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or diethyl ether), and other relevant parameters is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as an easily oxidized and highly volatile organometallic compound, it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions to maintain stability. The storage area should be cool, dry, and well-ventilated, away from moisture and incompatible materials such as strong acids or oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identity (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.