Description

(3-(1-Piperidinylmethyl)Phenyl)Magnesium Chloride is a highly reactive organomagnesium reagent, specifically an aryl Grignard reagent, essential for advanced organic synthesis. Its core value lies in enabling the efficient formation of carbon-carbon bonds, a critical step in constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the (3-(1-piperidinylmethyl)phenyl) moiety into target molecules during the development of new drug candidates.
• Agrochemical Production: Used in the construction of complex molecules for novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the synthesis of specialized monomers or ligands for advanced polymers and catalytic systems.
• Cross-Coupling Reactions: Serves as a critical coupling partner in palladium-catalyzed reactions (e.g., Kumada coupling) to form biaryl structures.
• Nucleophilic Addition Reactions: Reacts with carbonyl compounds (ketones, aldehydes, esters) to form new alcohols and carboxylic acid derivatives.
• Fine Chemical Manufacturing: Facilitates the production of high-value, complex organic compounds used in flavors, fragrances, and electronic chemicals.

Basic Information

Item	Detail
Product Name	(3-(1-Piperidinylmethyl)Phenyl)Magnesium Chloride
CAS No.	480424-82-6
Molecular Formula	C12H16ClMgN
Molecular Weight	233.99 g/mol
Synonyms	(3-(Piperidin-1-ylmethyl)phenyl)magnesium chloride; 1-[3-(Chloromagnesio)benzyl]piperidine; 3-(Piperidin-1-ylmethyl)phenylmagnesium chloride; (3-Piperidin-1-ylmethyl-phenyl)-magnesium chloride; Grignard Reagent (3-Piperidin-1-ylmethyl-phenyl)MgCl; (3-((Piperidin-1-yl)methyl)phenyl)magnesium chloride; 3-(1-Piperidinylmethyl)benzenemagnesium chloride
EINECS	Contact for details

Quality Control

Every batch of our (3-(1-Piperidinylmethyl)Phenyl)Magnesium Chloride is manufactured and tested under stringent quality protocols to ensure consistency and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) that detail critical parameters such as concentration, purity, and reactivity. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) at temperatures between 2°C and 8°C. The storage area must be dry, well-ventilated, and free from sources of ignition or incompatible materials.

Specification

Item	Specification
Appearance	Solution (typically in THF or Ether)
Concentration	0.5 M - 2.0 M in solvent (Custom)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.