Description

(2-(1-Pyrrolidinylmethyl)Phenyl)Magnesium Chloride is a highly reactive organomagnesium reagent, specifically an aryl Grignard reagent. This compound is a critical building block in advanced organic synthesis, enabling the formation of new carbon-carbon bonds with high precision. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the (2-(1-pyrrolidinylmethyl)phenyl) moiety into target molecules during the development of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl group functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the creation of organic electronic materials, such as those used in OLEDs or semiconductors, where precise aryl group incorporation is necessary.
• Cross-Coupling Reactions: Acts as a coupling partner in reactions like Kumada, Negishi, or Suzuki-Miyaura cross-couplings to form biaryl structures.
• Nucleophilic Addition: Reacts with a wide range of electrophiles including carbonyl compounds (ketones, aldehydes), epoxides, and carbon dioxide to form new alcohols or carboxylic acids.

Basic Information

Item	Details
Product Name	(2-(1-Pyrrolidinylmethyl)Phenyl)Magnesium Chloride
CAS No.	480424-80-4
Molecular Formula	C11H14ClMgN
Molecular Weight	219.99 g/mol
Synonyms	(2-(Pyrrolidin-1-ylmethyl)phenyl)magnesium chloride; 1-[(2-Magnesiochlorobenzyl)]pyrrolidine; 2-(1-Pyrrolidinylmethyl)phenylmagnesium chloride; Grignard Reagent, (2-(1-Pyrrolidinylmethyl)Phenyl)MgCl; (2-(N-Pyrrolidinylmethyl)phenyl)magnesium chloride; (2-Pyrrolidin-1-ylmethyl-phenyl)-magnesium chloride; Magnesium, chloro[2-[(1-pyrrolidinyl)methyl]phenyl]-; (2-((Pyrrolidin-1-yl)methyl)phenyl)magnesium chloride
EINECS	Contact for details

Quality Control

Every batch of our (2-(1-Pyrrolidinylmethyl)Phenyl)Magnesium Chloride is manufactured and handled under strict inert atmosphere conditions to ensure reactivity and purity. We employ rigorous analytical techniques, including titration and GC/HPLC analysis, to verify concentration and identify potential impurities. A comprehensive Certificate of Analysis (COA) detailing assay, solvent content, and impurity profile is provided with each shipment to guarantee consistency and support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at 2-8°C. For long-term stability, storage at lower temperatures (e.g., -20°C) under inert gas is recommended. The container should be kept in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Solution (typically in THF or Diethyl Ether)
Concentration	0.5 M - 2.0 M in solvent (Custom concentrations available)
Assay (Titration)	≥ 95% (of stated concentration)
Solvent	Specified per batch (THF, Diethyl Ether, etc.)
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.