Description

(4-(1-Pyrrolidinylmethyl)Phenyl)Magnesium Chloride is a highly reactive Grignard reagent, a critical organometallic intermediate for constructing complex molecular architectures. Its value lies in enabling efficient carbon-carbon bond formation, a cornerstone of modern synthetic organic chemistry. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to introduce the (4-(1-pyrrolidinylmethyl)phenyl) moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders.
• Agrochemical Synthesis: Used in the production of novel herbicides and fungicides by introducing specific aromatic amine functionalities.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: A vital reagent in Negishi, Kumada, and other transition-metal-catalyzed cross-coupling reactions to create biaryl structures.
• Academic & Contract Research: A valuable tool for methodological development and complex molecule synthesis in research laboratories.

Basic Information

Product Name	(4-(1-Pyrrolidinylmethyl)Phenyl)Magnesium Chloride
CAS No.	480424-78-0
Molecular Formula	C11H14ClMgN
Molecular Weight	219.99 g/mol
Synonyms	(4-(Pyrrolidin-1-ylmethyl)phenyl)magnesium chloride; 1-[(4-(Chloromagnesio)phenyl)methyl]pyrrolidine; 4-(Pyrrolidin-1-ylmethyl)phenylmagnesium chloride; (4-(1-Pyrrolidinylmethyl)phenyl)magnesium chloride; Grignard reagent of 1-[(4-bromophenyl)methyl]pyrrolidine; p-(Pyrrolidinylmethyl)phenylmagnesium chloride
EINECS	Contact for details

Quality Control

Every batch of our (4-(1-Pyrrolidinylmethyl)Phenyl)Magnesium Chloride is manufactured and handled under strict inert atmosphere conditions to ensure reactivity and purity. We provide comprehensive quality assurance, with standard testing including titration for assay determination and impurity profiling. A Certificate of Analysis (COA) detailing batch-specific results is supplied with each shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at 2-8°C. For long-term stability, store in a freezer at -20°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Solution (typically in THF or Diethyl Ether)
Identification (IR)	Conforms
Assay (Titration)	0.5 M in THF (or as specified)
Purity (HPLC)	≥ 95% (by GC/HPLC of derived product)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.