Description

(4-(4-Morpholinylmethyl)Phenyl)Magnesium Bromide is a specialized organomagnesium reagent, commonly known as a Grignard reagent, featuring a functionalized aromatic ring. This compound is valued for its role as a key synthetic building block in advanced organic synthesis, enabling the formation of new carbon-carbon bonds. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for introducing the (4-morpholinylmethyl)phenyl moiety into target molecules during the development of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aromatic amine functionalities.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the creation of functionalized polymers and organic electronic materials where the morpholine group modifies solubility or electronic properties.
• Cross-Coupling Reactions: Acts as an efficient coupling partner in palladium-catalyzed reactions, such as Kumada couplings, for biaryl synthesis.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex dyes, flavors, and fragrances.

Basic Information

Product Name	(4-(4-Morpholinylmethyl)Phenyl)Magnesium Bromide
CAS No.	480424-75-7
Molecular Formula	C11H14BrMgNO
Molecular Weight	280.44 g/mol
Synonyms	[4-(Morpholin-4-ylmethyl)phenyl]magnesium bromide; 4-(4-Morpholinylmethyl)phenylmagnesium bromide; (4-Morpholin-4-ylmethyl-phenyl)-magnesium bromide; 4-Morpholinomethylphenylmagnesium bromide solution; Grignard Reagent (4-Morpholinomethylphenyl)magnesium bromide; p-(Morpholinomethyl)phenylmagnesium bromide; 1-[4-(Morpholin-4-ylmethyl)phenyl]magnesium bromide
EINECS	Contact for details

Quality Control

Every batch of our (4-(4-Morpholinylmethyl)Phenyl)Magnesium Bromide is manufactured and handled under strict quality protocols. We ensure consistent reactivity and purity through rigorous in-process controls and final analytical testing, including titration for Grignard concentration and GC/HPLC analysis for solvent and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions, or as specified on the label. The storage area should be cool, dry, and well-ventilated, away from sources of ignition and incompatible materials such as acids, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Concentration (in THF or Ether)	0.5 M - 1.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR / NMR)	Conforms to structure
Water Content (Karl Fischer)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.