Description

Poly D(C-T) CAS NO 49717-92-2 is a synthetic oligonucleotide building block, specifically a dimer phosphoramidite, designed for automated solid-phase DNA synthesis. This high-purity chemical intermediate is critical for ensuring the fidelity and yield of custom oligonucleotide sequences. It is an essential raw material for research institutions, diagnostic kit manufacturers, and biotechnology companies engaged in PCR assay development, gene synthesis, and antisense oligonucleotide production.

Application

• Oligonucleotide Synthesis: As a phosphoramidite monomer for the automated synthesis of DNA strands in research and commercial settings.
• PCR Primer & Probe Manufacturing: For the production of specific primers and fluorescent probes used in molecular diagnostics and life science research.
• Antisense & siRNA Development: A key component in the synthesis of therapeutic oligonucleotides targeting gene expression.
• Gene Synthesis & Cloning: Used in the construction of synthetic genes, gene fragments, and mutagenesis studies.
• Diagnostic Assay Kits: Integral to manufacturing components for in vitro diagnostic (IVD) tests, including those for infectious diseases and genetic disorders.
• Next-Generation Sequencing (NGS): For creating custom adapters, barcodes, and other oligonucleotide tools used in sequencing workflows.

Basic Information

Item	Details
Product Name	Poly D(C-T) CAS NO 49717-92-2
CAS No.	49717-92-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	D(C-T) Phosphoramidite; Cytidine-Thymidine Dimer Phosphoramidite; 5'-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidylyl-(3'→5')-thymidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; dC-dT Dimer; DNA Dimer C-T; DMT-dC(bz)-dT-CE Phosphoramidite; Oligonucleotide Building Block C-T
EINECS	Contact for details

Quality Control

Our Poly D(C-T) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for oligonucleotide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee lot-to-lot consistency and performance reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C ± 5°C under anhydrous conditions. The product is hygroscopic (moisture-sensitive) and must be handled in a dry atmosphere or with proper desiccant protection to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.