Description

Thioinosine Triphosphate Disulfide is a chemically modified nucleotide analog of significant interest in biochemical and pharmaceutical research. This compound serves as a critical tool for studying enzyme mechanisms, particularly those involving ATP-dependent processes and redox biology. It is primarily utilized by research institutions and biotechnology companies engaged in nucleotide metabolism studies, antiviral research, and the development of novel diagnostic assays. The product is supplied to meet the stringent purity requirements of advanced life science applications.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases, ATPases, and other nucleotide-binding proteins.
• Antiviral Drug Discovery: Investigated for its potential role as a prodrug or metabolic intermediate in the development of nucleoside analog therapeutics.
• Diagnostic Assay Development: Employed in the formulation of specialized reagents for detecting specific enzymatic activities or metabolic pathways.
• Redox Signaling Studies: Acts as a probe to understand the role of disulfide bonds and thiol chemistry in cellular signaling and regulation.
• Nucleotide Metabolism Analysis: Serves as a reference standard or tracer in metabolic flux studies using techniques like HPLC or mass spectrometry.

Basic Information

Product Name	Thioinosine Triphosphate Disulfide
CAS No.	41486-94-6
Molecular Formula	C10H14N4O13P3S2
Molecular Weight	587.23 g/mol
Synonyms	6-Thioinosine Triphosphate Disulfide; 6-Mercaptopurine Riboside Triphosphate Disulfide; ITP Disulfide; 6-Thio-ITP Disulfide; Thio-ITP; Inosine 5'-(Tetrahydrogen Triphosphate), 6-thio-, disulfide; 6-Thioinosine 5'-triphosphate disulfide
EINECS	Contact for details

Quality Control

Our Thioinosine Triphosphate Disulfide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic identification (UV, NMR). A detailed Certificate of Analysis (COA) providing lot-specific data is available upon request, supporting compliance with internal quality standards for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term stability, store under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.