Description

8-Azidoadenosine is a chemically modified nucleoside analog, a crucial building block in bioorthogonal chemistry and bioconjugation. Its value lies in the highly reactive azido group, which enables efficient, selective, and biocompatible "click chemistry" reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC). This compound is essential for researchers and manufacturers in pharmaceutical development, proteomics, and chemical biology, where it is used for labeling, tracking, and functionalizing biomolecules like nucleic acids and proteins.

Application

• Bioconjugation & Probe Synthesis: Acts as a key reagent for site-specifically attaching fluorophores, biotin, or other functional tags to adenosine-containing biomolecules via click chemistry.
• Nucleic Acid Labeling & Sequencing: Used in the development of next-generation sequencing (NGS) technologies and fluorescent in situ hybridization (FISH) probes for genomic research.
• Proteomics & Target Identification: Serves as a photoaffinity labeling probe to capture and identify protein targets and study protein-nucleic acid interactions.
• Antiviral & Anticancer Research: Investigated as a potential prodrug or metabolic inhibitor in the development of novel therapeutic agents.
• Material Science & Surface Functionalization: Enables the modification of surfaces (e.g., chips, nanoparticles) with bioactive nucleosides for biosensor and diagnostic device development.
• Chemical Biology Tool Development: A fundamental component in toolkit expansions for studying cellular processes, metabolic pathways, and enzyme mechanisms.

Basic Information

Product Name	8-Azidoadenosine
CAS No.	4372-67-2
Molecular Formula	C10H12N8O4
Molecular Weight	308.26 g/mol
Synonyms	8-Azido-9-β-D-ribofuranosyl-9H-purin-6-amine; 8-Azidoadenine riboside; 8-N3-Adenosine; 8-Azido adenosine; Adenosine, 8-azido-; 6-Amino-8-azido-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our 8-Azidoadenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the product label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.