Description

Pth-L-Phenylalanine is a protected derivative of the essential amino acid L-Phenylalanine, where the amine group is blocked by a phthaloyl (Pth) protecting group. This modification is critical for enabling selective peptide synthesis and advanced organic transformations, ensuring reaction fidelity in complex molecular assembly. It serves as a vital building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for drug discovery and development.

Application

• Peptide Synthesis Intermediate: A key protected amino acid for solid-phase and solution-phase peptide synthesis, preventing unwanted side reactions.
• Pharmaceutical Research: Used in the development and production of peptide-based active pharmaceutical ingredients (APIs) and therapeutic candidates.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Acts as a chiral building block for the synthesis of complex organic molecules and specialty chemicals.
• Protecting Group Chemistry: Serves as a model compound in studies involving the introduction and removal of phthaloyl protecting groups.

Basic Information

Product Name	Pth-L-Phenylalanine
CAS No.	4332-97-2
Molecular Formula	C₁₇H₁₃NO₄
Molecular Weight	295.29 g/mol
Synonyms	N-Phthaloyl-L-phenylalanine; (S)-2-(1,3-Dioxoisoindolin-2-yl)-3-phenylpropanoic Acid; L-Phenylalanine, N-phthaloyl-; Phthaloyl-L-phenylalanine; N-Pth-L-Phe-OH; 2-[(S)-1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl]-3-phenylpropionic Acid; N-Phthalimido-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Pth-L-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.