Description

Pth-S-Carboxymethylcysteine is a key protected derivative of the amino acid cysteine, widely used as a crucial building block in peptide synthesis. Its primary value lies in providing a stable, protected form of the thiol group, preventing unwanted side reactions during complex peptide assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of therapeutic peptides and protein-based drugs.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the controlled, sequential addition of cysteine residues in automated peptide synthesis.
• Pharmaceutical Intermediates: Serves as a critical intermediate in the production of active pharmaceutical ingredients (APIs) for drugs targeting various diseases.
• Bioconjugation Chemistry: Used in the site-specific modification of proteins and peptides, enabling the creation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Research & Development: A vital tool in academic and industrial R&D labs for studying protein structure, function, and for novel drug discovery.
• Production of Cysteine Derivatives: Acts as a precursor for synthesizing other specialized, high-purity cysteine analogs and derivatives.

Basic Information

Product Name	Pth-S-Carboxymethylcysteine
CAS No.	29635-91-4
Molecular Formula	C12H12N2O5S
Molecular Weight	296.30 g/mol
Synonyms	N-[(Phenylthio)carbonyl]-S-carboxymethyl-L-cysteine; S-Carboxymethyl-N-(phenylthio)carbonyl-L-cysteine; PTC-CM-Cysteine; PTC-S-Carboxymethylcysteine; N-Phenylthiocarbamoyl-S-carboxymethylcysteine; L-Cysteine, S-carboxymethyl-, N-(phenylthio)carbonyl-; (2R)-2-[[(Phenylthio)carbonyl]amino]-3-[(carboxymethyl)sulfanyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Pth-S-Carboxymethylcysteine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Specific range available on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.