Description

Phenylthiohydantoin-Arginine Hydrochloride is a specialized derivative of arginine, a fundamental amino acid, modified with a phenylthiohydantoin group. This compound is of significant value in biochemical research and pharmaceutical development, particularly for its role in peptide sequencing and as a potential intermediate in the synthesis of more complex bioactive molecules. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in proteomics, analytical method development, and the production of high-purity reference standards.

Application

• Biochemical Research: A critical reagent in Edman degradation and other peptide/protein sequencing methodologies for the identification of arginine residues.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel peptide-based drugs and diagnostic agents.
• Analytical Reference Standards: Used as a high-purity standard for calibrating analytical instruments like HPLC and mass spectrometers in proteomic studies.
• Proteomics & Genomics: Employed in advanced research to study protein structure, function, and post-translational modifications.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of other specialized amino acid derivatives and labeled compounds.

Basic Information

Product Name	Phenylthiohydantoin-Arginine Hydrochloride
CAS No.	182153-75-9
Molecular Formula	C15H22N6O2S • HCl
Molecular Weight	394.91 g/mol (Free base: 350.44 g/mol)
Synonyms	PTH-Arginine HCl; 3-Phenyl-2-thiohydantoinyl-arginine hydrochloride; 2-[(5-Amino-1-{[(1S)-4-[(diaminomethylidene)amino]-1-carboxybutyl]carbamoyl}pentyl)imino]-5-phenyl-1,3-thiazolidin-4-one hydrochloride; Arginine phenylthiohydantoin hydrochloride; Edman degradation product of arginine
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin-Arginine Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.