Description

Pth-Tyrosine CAS NO 4332-95-0 is a protected derivative of the amino acid tyrosine, where the amine group is blocked by a phthaloyl (Pth) protecting group. This compound is a critical building block and intermediate in sophisticated organic synthesis, particularly in peptide chemistry and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for developing active pharmaceutical ingredients (APIs) and complex biomolecules.

Application

• Peptide Synthesis: Serves as a key protected amino acid intermediate in solid-phase and solution-phase peptide synthesis, preventing unwanted side reactions at the amine group.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides and protein-based drugs.
• Bioconjugation & Labeling: Acts as a precursor for creating labeled tyrosine derivatives used in biochemical assays and diagnostic tools.
• Chemical Biology Research: Employed in studies of enzyme mechanisms, protein-protein interactions, and signal transduction pathways.
• Fine Chemical Synthesis: Utilized as a chiral building block for the synthesis of non-peptidic compounds with biological activity.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Pth-Tyrosine
CAS No.	4332-95-0
Molecular Formula	C₁₇H₁₄N₂O₅
Molecular Weight	326.30 g/mol
Synonyms	N-Phthaloyl-L-tyrosine; (S)-2-(1,3-Dioxoisoindolin-2-yl)-3-(4-hydroxyphenyl)propanoic acid; L-Tyrosine, N-phthaloyl-; Phthaloyltyrosine; 2-[(2S)-2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid; N-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-L-tyrosine; PTH-Tyr-OH
EINECS	Contact for details

Quality Control

Our Pth-Tyrosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.