Description

Insulin, Ala(B0)- is a synthetic insulin analog characterized by a specific amino acid substitution. This engineered peptide is of significant interest in advanced pharmaceutical research and development, particularly for studying insulin receptor interactions and metabolic pathways. It serves as a critical intermediate or reference standard for biopharmaceutical companies, academic research institutions, and contract research organizations (CROs) focused on diabetes therapeutics and peptide chemistry.

Application

• Pharmaceutical R&D Intermediate: Used as a key building block in the research and development of novel insulin analogs and next-generation diabetes treatments.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate insulin signaling, receptor binding affinity, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and method development in HPLC, LC-MS, and other analytical techniques.
• Metabolic Studies: Utilized in preclinical research to model and understand specific metabolic effects related to insulin function.
• Peptide Synthesis & Conjugation: Acts as a starting material or model compound for further chemical modifications, labeling, or conjugation projects.

Basic Information

Product Name	Insulin, Ala(B0)-
CAS No.	100469-14-5
Molecular Formula	C257H383N65O77S6
Molecular Weight	~5807.9 g/mol
Synonyms	Ala(B0)-Insulin; Insulin Ala-B0; [AlaB0]-Insulin; B0-Alanine Insulin; Insulin analog (Ala B0); Insulin, B0-Ala-; Human Insulin Ala(B0) variant; Research Insulin Analog
EINECS	Contact for details

Quality Control

Our Insulin, Ala(B0)- is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management systems to guarantee traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept under desiccated conditions. For long-term storage, consider lyophilized (freeze-dried) form. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.