Description

Deoxyguanylyl-(3'-5')-deoxyadenosine is a defined dinucleotide, specifically a phosphodiester-linked deoxyguanosine-deoxyadenosine dimer. This compound is a critical building block and reference standard in molecular biology and biochemistry research. It is primarily utilized by researchers and manufacturers in the fields of oligonucleotide synthesis, nucleic acid chemistry, and pharmaceutical development, serving as a model compound for studying DNA structure, enzyme interactions, and for the calibration of analytical instruments.

Application

• Oligonucleotide Synthesis: Used as a controlled dimer unit or a reference standard in the solid-phase synthesis of custom DNA sequences.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies involving nucleases, polymerases, and ligases to understand DNA metabolism.
• Analytical Standard: Acts as a high-purity calibration standard for analytical techniques like HPLC, LC-MS, and capillary electrophoresis to ensure accuracy in nucleic acid analysis.
• Pharmaceutical Development: Employed in early-stage research for antisense oligonucleotides, aptamers, and other nucleic acid-based therapeutics.
• Diagnostic Probe Development: Utilized in the design and validation of specific DNA probes for genetic testing and molecular diagnostics.
• Academic & Educational Use: Provides a defined, pure compound for teaching advanced concepts in molecular biology and genetic engineering laboratories.

Basic Information

Product Name	Deoxyguanylyl-(3'-5')-Deoxyadenosine
CAS No.	4282-64-8
Molecular Formula	C20H25N10O10P
Molecular Weight	620.45 g/mol
Synonyms	d(GpA); Deoxyguanylyl-deoxyadenosine; dGpdA; Guanylyl(3'→5')adenosine deoxy; pdG-dA; Dinucleotide d(GpA); Deoxyguanosine 5'-monophosphate deoxyadenosine ester; 2'-Deoxyguanylyl-(3'→5')-2'-deoxyadenosine
EINECS	Contact for details

Quality Control

Our Deoxyguanylyl-(3'-5')-deoxyadenosine is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results from HPLC, NMR, and MS are available for every lot to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.