Description

Mitomycin B is a potent antibiotic and antitumor agent belonging to the mitomycin family of compounds. Its primary value lies in its ability to function as a bioreductive alkylating agent, cross-linking DNA and inhibiting cellular proliferation. This makes it a critical compound for research in oncology, biochemistry, and pharmacology. Researchers and manufacturers in the pharmaceutical and biotechnology sectors require high-purity Mitomycin B for developing novel therapeutics and conducting advanced biological studies.

Application

• Anticancer Research: Used as a reference standard and active agent in studies targeting DNA replication and tumor cell apoptosis.
• Biochemical Mechanism Studies: Employed to investigate bioreductive activation pathways and DNA alkylation processes.
• Pharmaceutical Intermediate: Serves as a key starting material or reference compound in the synthesis and development of novel chemotherapeutic agents.
• Microbiological Research: Acts as a potent antibiotic in studies concerning bacterial growth inhibition and mechanism of action.
• Cell Biology: Utilized in vitro to study cell cycle arrest, genotoxicity, and cellular response to DNA damage.
• Analytical Standard: Essential for quality control and method development in HPLC, LC-MS, and other analytical techniques within pharmaceutical labs.

Basic Information

Product Name	Mitomycin B
CAS No.	4055-40-7
Molecular Formula	C16H19N3O6
Molecular Weight	349.34 g/mol
Synonyms	7-Aminomitomycin; Mitomycin B; Antibiotic MA 56; NSC 70485; 6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione carbamate (ester); MA 56; Mitomycin B (antibiotic)
EINECS	Contact for details

Quality Control

Our Mitomycin B is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Blue to purple crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.