Description

Adenylyl-(3'-5')-Adenylyl-(3'-5')-Adenylyl-(3'-5')-Adenosine CAS NO 4042-12-0 is a defined-sequence trinucleotide, specifically a linear trimer of adenosine monophosphate linked by 3'-5' phosphodiester bonds. This high-purity biochemical is critical for research in molecular biology, enzymology, and nucleic acid chemistry, serving as a precise substrate or model compound. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical R&D departments focusing on RNA metabolism, enzyme kinetics, and oligonucleotide synthesis.

Application

• Enzymatic Substrate: Used as a specific substrate for studying ribonucleases, phosphodiesterases, and other nucleolytic enzymes to understand cleavage specificity and kinetics.
• Nucleic Acid Research: Serves as a model short oligonucleotide for investigating RNA structure, stability, and hybridization properties.
• Biochemical Assay Development: Employed in the development and calibration of assays for enzyme activity, particularly those involved in RNA processing and degradation pathways.
• Reference Standard: Acts as a high-purity chromatographic or spectroscopic standard for the quality control of synthetic oligonucleotides and related biochemicals.
• Primer/Template Studies: Utilized in foundational studies on primer extension reactions and template-directed synthesis with polymerases.
• Teaching & Training: Provides a well-defined compound for educational purposes in advanced biochemistry and molecular biology courses.

Basic Information

Product Name	Adenylyl-(3'-5')-Adenylyl-(3'-5')-Adenylyl-(3'-5')-Adenosine
CAS No.	4042-12-0
Molecular Formula	C30H37N15O19P3
Molecular Weight	1000.64 g/mol
Synonyms	Adenosine 5'-(triphosphoryl-3'-adenylyl-3'-adenylyl-3'-adenosine); pppA2'p5'A2'p5'A; 5'-Triphosphoryladenylyl-(3'→5')-adenylyl-(3'→5')-adenosine; 2-5A trimer; 2',5'-Oligoadenylate trimer; (2'-5')(A)3; 2',5'-PPP-A2'p5'A2'p5'A; 5'-O-[(Phosphonooxy)phosphinyl]adenylyl-(3'→5')-adenylyl-(3'→5')-adenosine
EINECS	Contact for details

Quality Control

Our Adenylyl-(3'-5')-Adenylyl-(3'-5')-Adenylyl-(3'-5')-Adenosine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via mass spectrometry. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability and compliance with your research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0 %
Extinction Coefficient (ε260)	Contact for details
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.