Description

Dusq1 Phosphoramidite CAS NO 374591-94-3 is a high-purity, specialized phosphoramidite monomer essential for the automated synthesis of oligonucleotides. This compound is critical for ensuring high coupling efficiency and sequence fidelity in the production of DNA and RNA strands. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and diagnostic sectors for applications in antisense therapy, PCR primers, and next-generation sequencing.

Application

• Solid-Phase Oligonucleotide Synthesis: As a key building block in automated DNA/RNA synthesizers for research and therapeutic oligonucleotide production.
• Antisense and siRNA Therapeutics: For the manufacture of oligonucleotide-based drugs targeting specific gene expression.
• Diagnostic Probe Development: Used in creating labeled probes for PCR, qPCR, and microarray technologies.
• Next-Generation Sequencing (NGS): Synthesis of primers and adapters essential for library preparation and sequencing workflows.
• Academic and Industrial R&D: Fundamental research in molecular biology, genetics, and synthetic biology.
• Custom Oligo Service Providers: Enabling high-throughput, reliable synthesis of custom DNA/RNA sequences for clients.

Basic Information

Product Name	Dusq1 Phosphoramidite
CAS No.	374591-94-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dusq1-CE Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-Dusq1-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dusq1 Phosphoramidite (DMTr protected); Dusq1-CE Phosphoramidite (Fast Deprotection); Dusq1 Deoxyribonucleoside Phosphoramidite; Dusq1-CE Phosphoramidite for DNA synthesis; Dusq1 nucleoside phosphoramidite
EINECS	Contact for details

Quality Control

Our Dusq1 Phosphoramidite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for oligonucleotide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.