Description

3,5-Dimethoxyphenylmagnesium Bromide is a highly reactive Grignard reagent, a critical organometallic building block for advanced organic synthesis. Its value lies in enabling the efficient formation of carbon-carbon bonds, specifically for introducing the 3,5-dimethoxyphenyl moiety into complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to synthesize active pharmaceutical ingredients (APIs), specialty chemicals, and functional organic intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing complex drug molecules, particularly those requiring aryl ether or dimethoxybenzene scaffolds.
• Agrochemical Production: Used in the synthesis of herbicides, fungicides, and plant growth regulators that incorporate dimethoxyphenyl groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine or N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Material Science Research: Building block for organic semiconductors, liquid crystals, and polymers with specific optical or electronic properties.
• Fine Chemical Manufacturing: Employed in the custom synthesis of specialty aromatics and complex organic compounds for various industrial applications.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic chemistry and exploratory synthesis projects.

Basic Information

Product Name	3,5-Dimethoxyphenylmagnesium Bromide
CAS No.	322640-05-1
Molecular Formula	C8H9BrMgO2
Molecular Weight	241.36 g/mol
Synonyms	Magnesium, bromo(3,5-dimethoxyphenyl)-; (3,5-Dimethoxyphenyl)magnesium bromide; 3,5-Dimethoxybenzene magnesium bromide; 3,5-Dimethoxyphenyl Grignard reagent; 1-Bromo-3,5-dimethoxybenzene magnesium; Grignard reagent 3,5-dimethoxyphenylMgBr; 3,5-Dimethoxybenzylmagnesium bromide (common misnomer); 3,5-Dimethoxyphenyl magnesium bromide solution
EINECS	Contact for details

Quality Control

Our 3,5-Dimethoxyphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing concentration, purity, and solvent specifications. We adhere to cGMP principles where applicable, and our quality systems are designed to support regulatory filings in the pharmaceutical and agrochemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions, or as specified on the label. Keep away from moisture, heat, and incompatible materials such as acids, oxidizers, and protic solvents. Use appropriate ventilation and explosion-proof equipment in storage areas.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom)
Assay (Titration)	≥ 95% (of stated concentration)
Identification (IR/NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.