Description

3-Methyl-2-Pyridylzinc Bromide is a highly reactive organozinc reagent, specifically a pyridylzinc halide, widely used in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and reliable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the 3-methyl-2-pyridyl moiety into target molecules via Negishi, Kumada, or other transition-metal-catalyzed cross-coupling reactions.
• Agrochemical Active Ingredient Development: Used in the research and scale-up of novel herbicides, fungicides, and insecticides that incorporate functionalized pyridine rings.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized pyridine-containing ligands used in homogeneous catalysis.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs or conductive polymers, where pyridine derivatives are common structural components.
• Fine Chemical and Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of complex organic molecules.

Basic Information

Product Name	3-Methyl-2-Pyridylzinc Bromide
CAS No.	308795-91-7
Molecular Formula	C6H6BrNZn
Molecular Weight	221.41 g/mol
Synonyms	2-(3-Methylpyridin-2-yl)zinc bromide; Zinc, bromo(3-methyl-2-pyridinyl)-; (3-Methyl-2-pyridinyl)zinc bromide; 3-Methyl-2-pyridylzinc bromide solution; 2-Pyridylzinc bromide, 3-methyl-; Bromo(3-methyl-2-pyridinyl)zinc
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-2-Pyridylzinc Bromide is manufactured and handled under strict inert atmosphere conditions to ensure stability and reactivity. We employ advanced analytical techniques, including NMR titration and ICP-MS, to verify concentration, purity, and the absence of detrimental impurities. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly moisture-sensitive (hygroscopic) and air-sensitive (easily oxidized) nature, this product must be stored under an inert atmosphere (argon or nitrogen) at 2-8°C. The container should be kept in a cool, dry, well-ventilated place, away from incompatible materials. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (Typical)	0.5 M in THF/Toluene or as specified
Assay (Zn titration)	≥ 95%
Identification (NMR)	Conforms to structure
Purity (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.