Description

3-Bromobenzylzinc Bromide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically through palladium-catalyzed cross-coupling reactions like Negishi coupling. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require the precise introduction of the 3-bromobenzyl moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted benzyl groups.
• Negishi Cross-Coupling Reactions: Serves as a highly reactive organozinc donor for coupling with various aryl, heteroaryl, and vinyl halides under palladium catalysis.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where specific benzyl modifications are required.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Facilitates the creation of functionalized organic molecules for use in organic light-emitting diodes (OLEDs) and other electronic materials.
• Custom Chemical Synthesis: Provides a reliable route for contract research organizations (CROs) and fine chemical producers to build complex, bespoke organic molecules.

Basic Information

Product Name	3-Bromobenzylzinc Bromide
CAS No.	307496-31-7
Molecular Formula	C7H6Br2Zn
Molecular Weight	313.32 g/mol
Synonyms	(3-Bromobenzyl)zinc bromide; Zinc, bromo(3-bromophenyl)methyl-; 3-Bromobenzylzinc bromide solution; (3-Bromobenzyl)zinc bromide solution; 1-Bromo-3-(bromozinciomethyl)benzene; Bromo(3-bromobenzyl)zinc; (m-Bromobenzyl)zinc bromide
EINECS	Contact for details

Quality Control

Every batch of our 3-Bromobenzylzinc Bromide is manufactured and tested under stringent quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and consistency for your critical synthetic applications. A detailed Certificate of Analysis (COA) including assay (by titration), zinc content, and halide content is supplied with each shipment to guarantee it meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), this reagent must be stored under a dry, inert gas (argon or nitrogen) in a cool, dry place. For solutions, ensure the container is securely sealed to prevent solvent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF)
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Zinc Content	Conforms
Bromide Content	Conforms
Identity (NMR)	Conforms to reference spectrum

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.