Description

Carubicin CAS NO 39472-31-6 is an anthracycline antibiotic and a key analog of the widely used chemotherapeutic agent, Daunorubicin. This compound is of significant interest in pharmaceutical research and development due to its potent antitumor properties. It serves as a critical intermediate and reference standard for researchers and manufacturers in the oncology and life sciences sectors, enabling the study of anticancer mechanisms and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced anthracycline-based chemotherapeutic agents.
• Biochemical Research: Used as a reference standard and active compound in studies investigating DNA intercalation, topoisomerase II inhibition, and mechanisms of cytotoxicity.
• Oncology Drug Development: Employed in preclinical research for evaluating the efficacy and structure-activity relationships (SAR) of novel anticancer compounds.
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical manufacturing.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and cancer biology.

Basic Information

Product Name	Carubicin
CAS No.	39472-31-6
Molecular Formula	C26H27NO10
Molecular Weight	513.49 g/mol
Synonyms	Carminomycin I; 4-Demethoxy-13-dihydrodaunorubicin; 4-Demethoxy-13-dihydrodaunomycin; NSC-180024; Antibiotic MA 144 M1; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
EINECS	Contact for details

Quality Control

Our Carubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Assay (HPLC)	95.0% - 105.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.