Description

3-Methoxyphenylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis for the formation of carbon-carbon bonds. Its primary value lies in its ability to introduce the 3-methoxyphenyl moiety into target molecules, enabling the synthesis of complex intermediates for pharmaceuticals and advanced materials. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for active pharmaceutical ingredients (APIs), particularly those containing substituted phenyl rings.
• Agrochemical Production: Used in the manufacture of herbicides, fungicides, and insecticides that require specific aromatic ether functionalities.
• Material Science Research: Employed in the synthesis of organic ligands for catalysts, liquid crystals, and advanced polymeric materials.
• Fine Chemical Manufacturing: Facilitates the production of dyes, pigments, and flavor & fragrance compounds through nucleophilic addition reactions.
• Academic & Industrial R&D: A fundamental tool for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	3-Methoxyphenylmagnesium Bromide
CAS No.	36282-40-3
Molecular Formula	C7H7BrMgO
Molecular Weight	211.34 g/mol
Synonyms	m-Methoxyphenylmagnesium Bromide; (3-Methoxyphenyl)magnesium Bromide; Magnesium, Bromo(3-methoxyphenyl)-; 3-Methoxybenzene, bromomagnesio-; 3-Methoxybenzylmagnesium Bromide (common misnomer); 3-Methoxy-Grignard Reagent; 3-Anisylmagnesium Bromide
EINECS	Contact for details

Quality Control

Our 3-Methoxyphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Each lot undergoes comprehensive analysis, including titration for Grignard concentration and impurity profiling. Certificates of Analysis (COA) detailing concentration, solvent, and typical impurity levels are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. Keep the container in a cool, dry, well-ventilated place, away from moisture, heat, and incompatible materials such as strong acids and oxidizers.

Specification

Item	Specification
Appearance	Clear, brownish to gray solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Identification (IR / NMR)	Conforms to structure
Water Content (Karl Fischer)	< 100 ppm
Solvent	Specified (Typically Tetrahydrofuran or Diethyl Ether)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.