Description

3-Benzyloxyphenylmagnesium Bromide, 1M is a high-purity Grignard reagent solution, a critical organometallic intermediate for advanced chemical synthesis. This compound matters for its role in forming new carbon-carbon bonds, enabling the construction of complex molecular architectures with high precision. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing key intermediates. The product is supplied as a standardized 1M solution in THF or diethyl ether for consistent, reliable performance in demanding synthetic applications.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for the production of active pharmaceutical ingredients (APIs), especially those containing biphenyl or substituted phenyl motifs.
• Agrochemical Development: Used in the research and scale-up of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for sophisticated phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Cross-Coupling Reactions: A vital reagent in Kumada, Negishi, and other palladium-catalyzed cross-coupling methodologies.
• Nucleophilic Aromatic Substitution: Facilitates the introduction of the benzyloxyphenyl moiety into various electrophilic aromatic systems.

Basic Information

Product Name	3-Benzyloxyphenylmagnesium Bromide, 1M
CAS No.	36281-96-6
Molecular Formula	C13H11BrMgO
Molecular Weight	287.43 g/mol
Synonyms	(3-(Benzyloxy)phenyl)magnesium bromide; 3-(Phenylmethoxy)phenylmagnesium bromide; 3-Benzyloxyphenylmagnesium Bromide solution; 1M 3-Benzyloxyphenylmagnesium Bromide in THF; Grignard reagent 3-BnOC6H4MgBr; Magnesium, bromo[3-(phenylmethoxy)phenyl]-; 3-(Benzyloxy)phenylmagnesium Bromide 1.0M in Diethyl Ether
EINECS	Contact for details

Quality Control

Every batch of our 3-Benzyloxyphenylmagnesium Bromide solution is manufactured and tested under stringent quality management systems. We ensure compliance with relevant industry standards for high-purity organometallic reagents. Comprehensive in-process and final release testing, including titration for assay/concentration and analysis of key impurities, is performed. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This product is easily oxidized and highly volatile. Keep away from heat, sparks, open flames, and strong oxidizing agents. The container must be kept tightly sealed in a dry, well-ventilated place. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress and pressure differential.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration	1.0 M (in THF or Diethyl Ether)
Assay (Titration)	0.95 - 1.05 M
Identification (IR)	Conforms to structure
Water Content (KF)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.