Description

3-Chlorophenylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis for the formation of carbon-carbon bonds. Its value lies in its ability to introduce the 3-chlorophenyl moiety into target molecules, enabling the synthesis of complex intermediates for pharmaceuticals and advanced materials. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating active pharmaceutical ingredients (APIs), particularly those containing chlorinated aromatic structures.
• Agrochemical Manufacturing: Used in the production of herbicides, fungicides, and insecticides where the 3-chlorophenyl group is a critical functional unit.
• Material Science Research: Employed in the synthesis of novel polymers, liquid crystals, and organic electronic materials.
• Fine Chemical Production: Serves as a reagent for the preparation of specialty chemicals, dyes, and pigments.
• Cross-Coupling Reactions: Acts as a nucleophile in palladium-catalyzed reactions like Kumada coupling to form biaryl compounds.
• Academic & Industrial R&D: A fundamental tool in research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	3-Chlorophenylmagnesium Bromide
CAS No.	36229-42-2
Molecular Formula	C6H4ClMgBr
Molecular Weight	215.75 g/mol
Synonyms	(3-Chlorophenyl)magnesium bromide; m-Chlorophenylmagnesium bromide; 1-Chloro-3-(bromomagnesio)benzene; Magnesium, bromo(3-chlorophenyl)-; Grignard reagent, 3-chlorophenylmagnesium bromide; 3-Chloro-phenylmagnesium bromide; m-Chloro-phenylmagnesium bromide
EINECS	Contact for details

Quality Control

Our 3-Chlorophenylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Quality is verified through analytical techniques including titration and GC analysis to confirm concentration and purity in solution. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and reacts violently with water and protic solvents. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area. Typical storage temperature is 2-8°C for extended stability. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Brown to dark brown solution
Concentration (in THF or Diethyl Ether)	Typically 0.5 M - 2.0 M
Assay (by Titration)	≥ 95% (of stated concentration)
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.