Description

Chloropropoxymagnesium is a highly reactive organomagnesium reagent, specifically a Grignard reagent derivative, widely utilized in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile and strong base for the formation of carbon-carbon bonds, a cornerstone reaction in constructing complex molecular frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and efficient synthetic methodologies.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the chloropropoxy moiety or for nucleophilic addition reactions in the production of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and plant growth regulators that require specific alkoxy or haloalkoxy functional groups.
• Fine Chemical Production: Employed in the synthesis of complex molecules, including flavors, fragrances, and advanced material precursors.
• Polymer Chemistry: Can serve as an initiator or modifying agent in the synthesis of specialized polymers and copolymers.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory synthesis in laboratory settings.
• Cross-Coupling Reactions: Potentially useful as a transmetalation agent in various palladium- or nickel-catalyzed cross-coupling protocols.

Basic Information

Item	Details
Product Name	Chloropropoxymagnesium
CAS No.	34259-73-9
Molecular Formula	C3H6ClMgO
Molecular Weight	117.83 g/mol
Synonyms	Magnesium, chloropropoxy-; 1-Chloropropoxymagnesium; 3-Chloropropoxymagnesium; Chloropropoxy magnesium; Propoxymagnesium chloride; Grignard reagent, chloropropoxy-; (3-Chloropropoxy)magnesium; Chloro(propoxy)magnesium
EINECS	Contact for details

Quality Control

Our Chloropropoxymagnesium is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through rigorous analytical testing, including titration for assay and monitoring of reactive impurities. A comprehensive Certificate of Analysis (COA) detailing purity, concentration (typically supplied in a specified solvent like THF or diethyl ether), and other critical parameters is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Isolate from incompatible materials such as acids, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR / NMR)	Conforms to structure
Assay (Titration)	0.5 M to 2.0 M in specified solvent
Solvent	Tetrahydrofuran (THF), Diethyl ether, or other
Purity (GC / HPLC)	≥ 95% (on solvent-free basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.