Description

17,21-[(tert-Butylboranediyl)Bisoxy]-11β-Hydroxypregn-4-Ene-3,20-Dione is a high-purity, advanced pharmaceutical intermediate of significant synthetic interest. This compound is a key building block in the synthesis of complex steroid derivatives and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel corticosteroid analogs and other steroidal pharmaceuticals.
• Research & Development: Used in academic and industrial R&D laboratories for exploring new synthetic pathways and studying structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a specialized starting material for the production of high-value, complex organic molecules in custom synthesis projects.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use as a tool compound in biochemical assays to investigate steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	17,21-[(tert-Butylboranediyl)Bisoxy]-11β-Hydroxypregn-4-Ene-3,20-Dione
CAS No.	30888-31-4
Molecular Formula	C₂₅H₃₉BO₅
Molecular Weight	430.39 g/mol
Synonyms	11β-Hydroxy-17,21-O-(tert-butylboranediyl)pregn-4-ene-3,20-dione; 11β-Hydroxyprednisolone 17,21-cyclic tert-butylboronate; Prednisolone 17,21-cyclic tert-butylboronate; 11β-Hydroxycortisone 17,21-cyclic tert-butylboronate; 17,21-(tert-Butylboranediyl)dioxyprednisolone; 30888-31-4; tert-Butylboronic ester of 11β-hydroxyprednisolone
EINECS	Contact for details

Quality Control

Every batch of 17,21-[(tert-Butylboranediyl)Bisoxy]-11β-Hydroxypregn-4-Ene-3,20-Dione is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.