Description

Polycytidylic Acid Potassium Salt is a polynucleotide composed of cytidine monophosphate units, widely utilized in biochemical and pharmaceutical research. Its primary value lies in its role as a synthetic RNA homopolymer, essential for studying nucleic acid interactions, enzyme mechanisms, and as a critical component in molecular diagnostics. This high-purity biochemical is indispensable for biotechnology companies, academic research institutions, and pharmaceutical developers focused on virology, immunology, and therapeutic oligonucleotide synthesis.

Application

• Molecular Biology Research: Used as a template or primer in enzymatic reactions, including reverse transcription and PCR-related studies.
• Virology & Immunology: Serves as a synthetic RNA analog to study viral replication mechanisms and to stimulate immune responses in experimental models.
• Diagnostic Reagent Manufacturing: A key raw material in the production of kits for nucleic acid detection and hybridization assays.
• Enzymology Studies: Employed as a substrate for enzymes such as ribonucleases, polymerases, and phosphorylases to investigate kinetics and specificity.
• Therapeutic Oligonucleotide Development: Acts as a building block or model compound in the research and development of antisense oligonucleotides and RNA-based therapeutics.
• Biophysical Research: Used to study the physical and chemical properties of nucleic acids, including hybridization dynamics and structural analysis.

Basic Information

Product Name	Polycytidylic Acid Potassium Salt
CAS No.	30811-80-4
Molecular Formula	(C9H12KN3O8P)n
Molecular Weight	Approx. 10,000 - 500,000 Da (varies by polymerization degree)
Synonyms	Poly(C) Potassium Salt; Potassium Polycytidylate; Polycytidylic Acid K+ Salt; Cytidine Homopolymer Potassium Salt; Poly rC Potassium Salt; 5'-Polycytidylic Acid Potassium Salt; Polynosinic:polycytidylic Acid Potassium Salt (related complex); Poly I:C Potassium Salt (related complex)
EINECS	Contact for details

Quality Control

Our Polycytidylic Acid Potassium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including assessment of polynucleotide chain length, purity, and identity, to ensure it meets the stringent requirements for life science research. A Certificate of Analysis (COA) detailing specific results for parameters such as UV absorbance profile, endotoxin levels, and bioburden is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to prevent degradation. For short-term use, aliquots may be stored at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (UV)	Characteristic absorbance maxima at ~268-272 nm
Assay (HPLC)	≥ 95% (Polycytidylic Acid basis)
Chain Length (SEC/GPC)	Specified range available (e.g., 100-500 bases)
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg
Solubility	Soluble in water and buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.