Description

Ara-Atp CAS NO 3714-60-1 is a synthetic nucleoside analog of adenosine triphosphate (ATP), where the ribose sugar is replaced by an arabinose moiety. This structural modification is critical for its role as a potent inhibitor of viral DNA polymerases and reverse transcriptases, making it a valuable research compound. It is primarily utilized by pharmaceutical researchers and biochemists in antiviral studies, enzyme kinetics research, and as a biochemical tool for probing nucleotide-dependent processes.

Application

• Antiviral Research: Serves as a key reference standard and active compound in studies targeting herpesviruses (HSV, CMV) and other DNA viruses due to its mechanism of chain termination.
• Biochemical Tool: Used in enzymatic assays to study the specificity and inhibition kinetics of viral and cellular polymerases.
• Nucleotide Metabolism Studies: Employed to investigate cellular pathways involving ATP analogs and nucleotide salvage mechanisms.
• Pharmaceutical Development: Acts as a lead compound or intermediate in the research and development of novel antiviral therapeutics.
• Academic Research: Utilized in university and institutional labs for fundamental research in virology, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Ara-Atp
CAS No.	3714-60-1
Molecular Formula	C10H16N5O12P3
Molecular Weight	507.19 g/mol
Synonyms	9-β-D-Arabinofuranosyladenine 5'-triphosphate; Ara-ATP; 1-(β-D-Arabinofuranosyl)adenine 5'-triphosphate; Vidarabine triphosphate; Arabinofuranosyladenine triphosphate; AraATP; 9-β-D-Arabinofuranosyl-9H-purin-6-amine 5'-(trihydrogen triphosphate)
EINECS	223-073-9

Quality Control

Our Ara-Atp is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store under inert atmosphere or desiccant.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Biological Activity	Tested in standard enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.