Description

Uridylyl-(3'-5')-Uridylyl-(3'-5')-3'-Uridylic Acid CAS NO 3504-15-2 is a defined dinucleotide derivative, specifically a uridylyl-uridylyl-uridine sequence, which serves as a critical building block and reference standard in nucleic acid research. This compound is essential for studying RNA structure, enzyme kinetics, and oligonucleotide synthesis pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on molecular biology and therapeutic development.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies of RNA ligases, polymerases, and nucleotidyltransferases.
• Oligonucleotide Synthesis: Serves as a protected intermediate or reference compound in the solid-phase synthesis of custom RNA sequences.
• Pharmaceutical Development: Employed in the research and development of antiviral and antisense oligonucleotide therapeutics.
• Diagnostic Assay Manufacturing: Acts as a critical raw material or calibration standard in the production of molecular diagnostic kits (e.g., PCR-based tests).
• Academic Research: Fundamental tool for investigating RNA splicing mechanisms, RNA-protein interactions, and nucleic acid metabolism.
• Quality Control Standard: Used as a high-purity reference material to validate analytical methods (HPLC, MS) for oligonucleotide-based products.

Basic Information

Product Name	Uridylyl-(3'-5')-Uridylyl-(3'-5')-3'-Uridylic Acid
CAS No.	3504-15-2
Molecular Formula	C27H33N9O22P2
Molecular Weight	857.55 g/mol
Synonyms	Uridylyl(3'→5')uridylyl(3'→5')uridine 3'-(dihydrogen phosphate); pU-U-U; Uridine 5'-[P1-(uridylyl)-P2-(uridylyl)] triphosphate; Uridylyl-uridylyl-uridine 3'-phosphate; U-U-U 3'-phosphate; 3'-Uridylic acid, uridylyl(3'→5')uridylyl(3'→5')-; Trinucleotide UpUpU; Uridine phosphates (UpUpU)
EINECS	Contact for details

Quality Control

Our Uridylyl-(3'-5')-Uridylyl-(3'-5')-3'-Uridylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, desiccate and keep under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.