Description

2,5-Dichlorobenzylmagnesium Chloride is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its value lies in its ability to introduce the 2,5-dichlorobenzyl group into a diverse array of electrophiles, enabling the synthesis of complex intermediates. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and scalable methods for constructing functionalized aromatic systems.

Application

• Key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those containing dichlorinated aromatic motifs.
• Building block for agrochemicals, such as herbicides and fungicides, where the 2,5-dichlorobenzyl moiety imparts specific biological activity.
• Precursor for the preparation of liquid crystals and other advanced organic electronic materials used in display technologies.
• Reagent in academic and industrial R&D laboratories for methodological development and the construction of novel chemical libraries.
• Used in coupling reactions (e.g., with carbonyl compounds, epoxides, or alkyl halides) to create new carbon-carbon bonds in fine chemical synthesis.

Basic Information

Product Name	2,5-Dichlorobenzylmagnesium Chloride
CAS No.	213627-19-1
Molecular Formula	C7H5Cl2MgCl (often represented as C7H5Cl2MgCl or in solution form)
Molecular Weight	Contact for details
Synonyms	2,5-Dichlorobenzylmagnesium Chloride; (2,5-Dichlorophenyl)methylmagnesium Chloride; Magnesium, chloro(2,5-dichlorobenzyl)-; 2,5-Dichlorobenzyl Grignard Reagent; 2,5-Dichlorobenzylmagnesium Chloride solution; (2,5-Dichlorobenzyl)magnesium chloride; 1-(Chloromagnesio)methyl-2,5-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 2,5-Dichlorobenzylmagnesium Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including titration for Grignard concentration and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration (typically provided as a solution in THF or other ethers), and relevant specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The storage area should be cool, dry, and well-ventilated, away from sources of ignition, moisture, and strong oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Colorless to light yellow or brown solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.