Description

N6-Benzoyl-2'-Deoxyadenosine is a chemically modified nucleoside derivative where a benzoyl group protects the N6 position of the adenine base. This compound is of significant value in oligonucleotide synthesis and pharmaceutical research as a key building block for creating modified DNA sequences. It is primarily needed by manufacturers and research institutions in the fields of antiviral drug development, antisense oligonucleotide therapeutics, and molecular biology research.

Application

• Phosphoramidite Synthesis: A crucial protected intermediate for the solid-phase synthesis of oligonucleotides and antisense drugs.
• Antiviral & Anticancer Prodrug Development: Used in the research and synthesis of nucleoside analog prodrugs targeting viral polymerases and cellular replication.
• Molecular Biology Research: Serves as a modified nucleotide for studying DNA-protein interactions, enzyme mechanisms, and nucleic acid chemistry.
• Diagnostic Probe Manufacturing: Employed in the creation of labeled DNA probes for genetic testing and diagnostic assays.
• Bioconjugation & Labeling: Acts as a starting material for attaching reporter molecules or other functional groups to nucleic acids.
• Academic & Industrial R&D: Fundamental research tool in chemistry and biochemistry laboratories for novel therapeutic and diagnostic platforms.

Basic Information

Product Name	N6-Benzoyl-2'-Deoxyadenosine
CAS No.	206752-42-3
Molecular Formula	C17H17N5O4
Molecular Weight	355.35 g/mol
Synonyms	2'-Deoxy-N6-benzoyladenosine; N6-Benzoyl-2'-deoxyadenosine; N6-Bz-dA; dA(Bz); 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-benzoylpurine; 2'-Deoxyadenosine, N6-benzoyl-; Bz-dA; N-Benzoyl-2'-deoxyadenosine
EINECS	Contact for details

Quality Control

Our N6-Benzoyl-2'-Deoxyadenosine is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.