Description

Pamam Dendrimer Generation 5.5 is a precisely engineered, hyperbranched polymer with a well-defined, globular architecture and a high density of surface functional groups. This structural precision makes it a critical advanced material for nanotechnology, drug delivery, and surface modification applications. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biomedical, and advanced materials sectors who require a consistent, high-purity scaffold for conjugation and controlled assembly.

Application

• Drug Delivery & Nanomedicine: Acts as a versatile nanocarrier for the encapsulation or covalent attachment of therapeutic agents (drugs, genes, siRNA), enhancing solubility, targeting, and controlled release.
• Diagnostic Agent Carrier: Serves as a platform for attaching contrast agents (e.g., for MRI) or fluorescent probes, creating multimodal imaging tools.
• Gene Transfection: Utilized as a non-viral vector for gene therapy, where its cationic surface groups facilitate complexation with nucleic acids for cellular delivery.
• Catalyst Support: Provides a high-surface-area, functionalized matrix for immobilizing metal nanoparticles or catalytic molecules, enhancing reaction efficiency and catalyst recovery.
• Surface Modification & Coatings: Used to create functional thin films or modify material surfaces to impart specific properties like hydrophilicity, anti-fouling, or adhesion promotion.
• Sensor Development: Employed as a scaffold to create highly sensitive chemical or biological sensors by attaching receptor molecules to its numerous terminal groups.
• Advanced Material Synthesis: Functions as a nanoscale building block or cross-linker in the synthesis of hybrid organic-inorganic composites and smart materials.

Basic Information

Product Name	Pamam Dendrimer Generation 5.5
CAS No.	202009-67-4
Molecular Formula	C622H1252N252O124
Molecular Weight	~14,000 g/mol (Theoretical)
Synonyms	PAMAM Dendrimer, G5.5; Poly(amidoamine) Dendrimer, Generation 5.5; Starburst Dendrimer, G5.5; PAMAM-OH Dendrimer; PAMAM Dendrimer with carboxylate surface groups; 5.5G PAMAM Dendrimer; PAMAM (G=5.5); Polypropylenimine hexadecaamine dendrimer (related class)
EINECS	Contact for details

Quality Control

Our Pamam Dendrimer Generation 5.5 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including size-exclusion chromatography (SEC/GPC) for molecular weight distribution, nuclear magnetic resonance (NMR) for structural confirmation and degree of branching, and titration for functional group analysis. A detailed Certificate of Analysis (COA) documenting purity, identity, and key specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C (refrigerated) or as indicated on the label. Allow the product to equilibrate to room temperature in the sealed container before opening to prevent moisture condensation. Store in a cool, dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid or viscous solution
Identification (NMR)	Conforms to structure
Purity (SEC)	≥ 95% (Dendrimer content)
Molecular Weight (GPC)	~14,000 Da (Theoretical, Mn)
Polydispersity Index (PDI)	≤ 1.05
Surface Group	Carboxylate (COO-)
Solvent (if supplied as solution)	Water, Methanol, or other (as specified)
Concentration (if supplied as solution)	As specified (e.g., 10 wt% in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.