Description

3-Chlorobenzylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its value lies in its ability to act as a powerful nucleophile and carbon nucleophile source for the formation of new carbon-carbon bonds, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing a substituted benzyl moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the 3-chlorobenzyl group imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of dyes, pigments, liquid crystals, and other performance chemicals.
• Academic and R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic and medicinal chemistry research.

Basic Information

Product Name	3-Chlorobenzylmagnesium Chloride
CAS No.	29874-01-9
Molecular Formula	C7H6Cl2Mg
Molecular Weight	185.33 g/mol
Synonyms	(3-Chlorophenyl)methylmagnesium Chloride; m-Chlorobenzylmagnesium Chloride; Magnesium, chloromethyl-3-chlorophenyl-; 3-Chlorobenzylmagnesium Chloride solution; Grignard reagent, 3-chlorobenzylmagnesium chloride; (3-Chlorobenzyl)magnesium Chloride; 1-Chloro-3-(chloromethyl)benzene magnesium complex
EINECS	Contact for details

Quality Control

Our 3-Chlorobenzylmagnesium Chloride is produced under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We employ advanced analytical techniques, including titration and GC/HPLC analysis, to verify concentration, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing assay, solvent content, and other relevant parameters is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) to prevent decomposition. For solutions, store at recommended temperatures (typically 2-8°C or as specified) in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow/brown
Concentration (in THF or Ether)	Typically 0.5M - 2.0M
Assay (by Titration)	≥ 95% (of stated concentration)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.