Description

2',3'-(O)-(4-(n-2-Chloroethyl-n-Methylamino)Benzylidene)Uridine-5'-Methylphosphate is a chemically modified nucleoside derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel therapeutic agents, particularly in the fields of oncology and antiviral drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of targeted nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of experimental anticancer and antiviral prodrugs.
• Biochemical Research: Used in studies investigating nucleotide metabolism, enzyme inhibition, and mechanism of action.
• Prodrug Development: Serves as a precursor for creating targeted drug delivery systems designed for selective activation.
• Antisense Oligonucleotide Synthesis: Potential use in the modification of oligonucleotides for therapeutic applications.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug efficacy and reduce toxicity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2',3'-(O)-(4-(n-2-Chloroethyl-n-Methylamino)Benzylidene)Uridine-5'-Methylphosphate
CAS No.	25878-32-4
Molecular Formula	C₂₀H₂₅ClN₃O₈P
Molecular Weight	477.85 g/mol
Synonyms	Uridine, 2',3'-O-[4-[bis(2-chloroethyl)amino]benzylidene]-5'-(methyl phosphate); 2',3'-O-(4-[Bis(2-chloroethyl)amino]benzylidene)uridine 5'-(methyl phosphate); 4-[Bis(2-chloroethyl)amino]benzaldehyde cyclic 2',3'-(methyl phosphate) with uridine; Uridine 5'-(methyl phosphate) 2',3'-(4-[bis(2-chloroethyl)amino]benzylidene) acetal; 25878-32-4; Chloroethylamino Benzylidene Uridine Methylphosphate
EINECS	Contact for details

Quality Control

Our 2',3'-(O)-(4-(n-2-Chloroethyl-n-Methylamino)Benzylidene)Uridine-5'-Methylphosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.