Description

Poly D(I-C) is a synthetic oligonucleotide sequence, a critical building block in molecular biology and genetic research. This product is essential for applications requiring high-fidelity DNA synthesis and precise genetic manipulation. It is primarily utilized by research institutions, diagnostic developers, and biotechnology companies engaged in PCR, gene synthesis, and probe development.

Application

• Polymerase Chain Reaction (PCR): Used as a primer or probe component for the amplification and detection of specific DNA sequences.
• Gene Synthesis & Cloning: Serves as a fundamental oligonucleotide building block for the *de novo* construction of synthetic genes and vectors.
• Diagnostic Assay Development: Integral to the design of probes for fluorescence *in situ* hybridization (FISH), microarrays, and other molecular diagnostic platforms.
• Antisense & RNAi Research: Acts as a component in the synthesis of antisense oligonucleotides or siRNA for gene silencing studies.
• Next-Generation Sequencing (NGS): Employed in the preparation of sequencing libraries, including adapter and barcode sequences.
• Biopharmaceutical R&D: Used in the research and development of oligonucleotide-based therapeutics, including aptamers.

Basic Information

Product Name	Poly D(I-C)
CAS No.	25853-45-6
Molecular Formula	C19H27N7O11P2 (monomer)
Molecular Weight	615.41 g/mol (monomer)
Synonyms	Poly(deoxyinosinic-deoxycytidylic) acid; Poly(dI-dC); Poly(dI-dC) double-stranded DNA; Poly(deoxyinosinic-deoxycytidylic) acid sodium salt; dI-dC copolymer; TLR3 agonist oligonucleotide; Synthetic double-stranded oligonucleotide
EINECS	Contact for details

Quality Control

Our Poly D(I-C) is manufactured under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and endotoxin levels. We adhere to ISO 9001 quality management principles, and our production environment is designed to meet the exacting standards of molecular biology research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a non-frost-free freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to prevent condensation. For long-term storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥ 95% (Oligonucleotide content)
Purity (HPLC)	≥ 90% (Full-length sequence)
Endotoxin Level (LAL)	< 10 EU/mg
Absorbance Ratio (A260/A280)	1.8 - 2.0
Solubility	Soluble in TE buffer or nuclease-free water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.