Description

Chloroethoxymagnesium is a versatile organomagnesium reagent, specifically a Grignard-type compound, widely used in organic synthesis. Its primary value lies in its ability to act as a powerful base and nucleophile for the formation of carbon-carbon and carbon-heteroatom bonds. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex molecular scaffolds, particularly in the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the production of herbicides, fungicides, and insecticides where specific alkylation or addition reactions are required.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, fragrances, and advanced materials.
• Polymer Chemistry: Acts as an initiator or catalyst component in certain polymerization processes for specialty polymers.
• Laboratory Research & Development: A valuable tool for organic chemists in academic and industrial R&D for exploring new synthetic pathways.
• Nucleophilic Addition Reactions: Facilitates the addition of ethoxy and alkyl groups to carbonyl compounds like ketones and aldehydes.

Basic Information

Product Name	Chloroethoxymagnesium
CAS No.	25764-17-4
Molecular Formula	C2H5ClMgO
Molecular Weight	104.81 g/mol
Synonyms	Ethoxychloromagnesium; Magnesium, chloroethoxy-; Chloro(ethoxy)magnesium; Ethylmagnesium Chloride Ethoxide Complex; Grignard Reagent (Ethoxy); (Ethoxy)magnesium chloride; Chloromagnesium ethoxide
EINECS	Contact for details

Quality Control

Our Chloroethoxymagnesium is produced under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We employ advanced analytical techniques, including titration and spectroscopic methods, to verify purity and composition. A Certificate of Analysis (COA) detailing specific results for each batch is available upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and highly volatile nature, this material must be stored under a dry, inert atmosphere (e.g., nitrogen or argon) in a cool, well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF or diethyl ether)
Identification (IR)	Conforms
Assay (Titration)	≥ 0.5 M to 3.0 M in specified solvent (Custom concentrations available)
Water Content (KF)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.